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Research

Health and Biotechnology

microglia cells

Overview

The skills of chemical engineers are uniquely suited to developing next-generation solutions to persistent health challenges. UW ChemE boasts strong cross-disciplinary collaborations with medical researchers in the design of smarter therapeutics, targeted drug delivery systems, and improved diagnostics. Our faculty also conduct research in systems and synthetic biology, as well as metabolic, biomolecular, and protein engineering.

Image: A Euclidean distance transform of a confocal microscopy image of microglia cells taken in a rat organotypic brain slice model. The colors are scaled to represent the distance away from a cell surface. Created by Chad Curtis for the 2019 Science & Engineering as Art Competition

Research Topics

  • Regenerative medicine
  • Neuromedicine
  • Nanomedicine
  • Metabolic engineering
  • Synthetic biology
  • Systems biology
  • Biomolecular engineering
  • Protein engineering
  • Environmental engineering
  • Medical diagnostics
  • Sensing technologies

Featured Research Clusters

Biomaterials
Faculty: Baneyx, DeForest, Nance, Ratner, Posner, Pozzo
With several field-defining visionaries in the biomedical sciences having cultivated their careers in UW ChemE, our department holds one of the longest and richest histories in biomaterial innovation. With creativity more fervent than ever, we employ current tools to engineer functional tissue, guide immune responses to medical implants, and probe stem cell fate in 4D.

Synthetic biology
Faculty: Bagheri, Beck, Carothers, DeForest, Marchand
Deciphering, retooling, and reinventing the tricks of basic biology, our faculty engineer versatile approaches to synthesize industrially and medically important chemicals and materials at scale. These efforts are complemented with advanced computational modeling to shed light on the inner workings of cellular bioprocesses.

Advanced therapeutic delivery
Faculty: DeForest, Nance, Ratner, Pozzo
From coercing nanoparticles past the blood-brain barrier, to identifying and treating disease with ultrasound theranostics, to confining therapeutic payload delivery to tissue-barcoded bodily locations, the University of Washington is developing real-world solutions to advance medical treatment. Studies are performed in close collaboration with field-leading partners in UW Medicine, Fred Hutch Cancer Research Center, and Seattle Children’s Hospital.

Campus Opportunities

Institute for Stem Cell and Regenerative Medicine
ISCRM's mission is to turn fundamental discoveries in stem cell science into therapies for patients

Center for Dialysis Innovation
CDI develops and tests novel treatment technologies in order to improve the health and well-being of people receiving dialysis therapy

Institute for Protein Design
The institute develops and applies methods for designing a whole new world of synthetic proteins to address today's complex challenges

Center for Synthetic Biology
The center's mission is to provide a collaborative and interdisciplinary environment for research, education, innovation, safety and responsibility in synthetic biology at the UW and in the Seattle area

Hollomon Health Innovation Challenge
The Hollomon Health Innovation Challenge is an entrepreneurship competition run by the UW Foster School of Business that gives students the opportunity to come up with meaningful solutions to big problems the world faces today related to health

Learn More

Careers in nanomedicine and drug delivery
By Elizabeth Nance

Related News

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Tue, 09/13/2022

Retooling microbes to upcycle CO2

An interdisciplinary, UW-led team of synthetic biologists will embark on a 5-year, $15 million project to engineer microbial genomes that transform CO2 into high-value chemicals.

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Tue, 05/17/2022 | UW Molecular Engineering & Sciences Institute

Unlocking biotechnology with RNA

Two recent molecular engineering alums, advised by ChemE professor James Carothers, have launched a startup to engineer 'smart' RNA to solve complex problems

Sydney Floryanzia

Tue, 04/19/2022 | AIChE CEP

Breaking down the blood-brain barrier

Ph.D. student Sydney Floryanzia is developing drug delivery methods to cross the blood-brain barrier. Inspired by music, great mentors, and the complexities of the brain, she's loving the work she does every day.

winning inSTENT Connection team with big check

Fri, 03/11/2022 | UW Foster School of Business

ChemE seniors part of winning health innovation team

Evan Ross and Jimmy Ye were part of team inSTENT Connection, which won the $15,000 grand prize in the Hollomon Health Innovation Challenge