Knowledge and solutions for a changing world
Research Associate Professor
Office: 257 Benson
- B.S., Nanjing University, 1985
- M.S., Nanjing University, 1989
- Ph.D., Cornell University, 1995.
- Postdoctoral Fellow, NASA JPL/CalTech, 1996.
- Nanomaterials, functional nanostructures, and nanocharacterization
- Optical and plasmonic biosensors
Nanomaterials, functional nanostructures, and nanocharacterization
Solid-state materials and structures at the nanoscale exhibit unique properties such as quantum confinement of electrons associated with semiconductor nanocrystals (e.g., quantum dots or nanowires) and electromagnetic field enhancement by localized surface plasmon resonance (LSPR) associated with metallic nanocrystals and nanostructues (e.g., particles, rods, rings, or holes). All of these nanomaterials and nanostructures have wide applications in photonic devices, solid-state lighting, solar cells, biomedical diagnostics and therapy, and chemical and biological sensing. We focus on a fundamental understanding of molecular-level material growth and processing mechanisms, the development and characterization of nanomaterials, and the engineering fabrication of functional nanostructures for energy and biological applications using an integrated experimental and computational approach.
Optical and plasmonic biosensors
Optical biosensors based on surface plasmon resonance (SPR) enable the direct observation of molecular interaction in real-time and offer the benefits of rapid, sensitive and label-free detection of chemical and biological species with potential applications in numerous important areas including medical diagnostics, food safety, security, and environmental monitoring. We focus on developing new surface chemistry and bioassay to provide specific detections and on integrating nanostructures to the sensor platform to enhance the detection sensitivity. Metallic nanoparticles and nanostructures have spurred great interest recently for biosensing because of the unique localized surface plasmon resonance (LSPR) excitations and have been used for LSPR sensor and field-enhanced Raman scattering (SERS). Our goals are to fundamentally understand the optical and plasmonic properties of rational designed nanostructures with different metallic and dielectric materials in order to achieve high sensitivity and strong enhancement and to develop label-free molecular specific biosensors by the integration of metallic nanostructures and microfluidics.
- Huang, C.H., Brault, N.D., Li, Y.T., Yu, Q.M., Jiang, S.Y. Controlled Hierarchical Architecture in Surface-initiated Zwitterionic Polymer Brushes with Structurally Regulated Functionalities. Advanced Materials 2012, 24(14): pp. 1834-1837.
- Brault, N.D., Sundaram, H.S., Li, Y.T., Huang, C.J., Yu, Q.M., Jiang, S.Y. Dry Film Refractive Index as an Important Parameter for Ultra-Low Fouling Surface Coating. Biomacromolecules 2012, 13(3): pp. 589-593.
- Zhang, L., Xu, J.J., Mi, L., Gong, H., Jiang, S.Y., Yu, Q.M. Multifunctional magnetic-plasmonic nanoparticles for fast concentration and sensitive detection of bacteria using SERS. Biosensors & Bioelectronics 2012, 31(1): pp. 130-136.
- Zhu, L., Richardson, B., Tanumihardja, J., Yu, Q.M. Controlling morphology and phase of pyrite FeS2 hierarchical particles via the combination of structure-direction and chelating agents. Crystengcomm 2012, 14(12): pp. 4188-4195.
- Xu, J.J., Kvasnicka, P., Idso, M., Jordan, R.W., Gong, H., Homola, J., Yu, Q.M. Understanding the effects of dielectric medium, substrate, and depth on electric fields and SERS of quasi-3D plasmonic nanostructures. Optics Express 2011, 19(21): pp. 20493-20505.
- Xu, J.J., Guan, P., Kvasnicka, P., Gong, H., Homola, J., Yu, Q.M. Light Transmission and Surface-Enhanced Raman Scattering of Quasi-3D Plasmonic Nanostructure Arrays with Deep and Shallow Fabry-Perot Nanocavities. Journal of Physical Chemistry C 2001, 115(22): pp. 10996-11002.
- Zhao, C., Li, L.Y., Wang, Q.M., Yu, Q.M., Zheng, J. Effect of Film Thickness on the Antifouling Performance of Poly(hydroxy-functional methacrylates) Grafted Surfaces. Langmuir 2011, 27(8): pp. 4906-4913.
- Xu, J.J., Zhang, L., Gong, H., Homola, J., Yu, Q.M. Tailoring Plasmonic Nanostructures for Optimal SERS Sensing of Small Molecules and Large Microorganisms. Small 2011, 7(3): pp. 371-376.
- Yu, Q.M., Braswell, S., Christin, B., Xu, J.J., Wallace, P.M., Gong, H., Kaminsky, D. Surface-enhanced Rama scattering on gold quasi-3D nanostructure and 2D nanohole arrays. Nanotechnology 2010, 21(35).
- Brault, N.D., Gao, C.L., Xue, H., Paillarik, M., Homola, J., Jiang, S.Y. Yu, Q.M. Ultra-low fouling and functionalizable zwitterionic coatings grafted onto SiO2 via a biomimetic adhesive group for sensing and detection in complex media. Biosensors & Bioelectronics 2010, 25(10): pp. 2276-2282.